churg strauss syndrome after polypectomy in asthmatic and allergic patients
نویسندگان
چکیده
churg strauss syndrome (css) is a form of primary vasculitis that is characterized by severe eosinophilia and often granulomatous inflammation as well as history of asthma or allergy. previously, the association between cysteinyl leukotrien receptor antagonists (ltras), corticosteroid withdrawal or a sudden change in its used method and css had been established. we report three cases that have been referred because of dyspnea, wheezing and cough with a history of allergic rhinitis and nasal polypectomy. after polypectomy, disseminated skin purpuric rashes appeared on their forelegs, abdomen and all of them had experienced neuropathic signs in their extremities. clinical findings, marked eosinophilia in blood and skin biopsies finally led to the diagnosis of css. the patients have been free of symptoms after receiving prednisolone; routine examinations and blood tests have rended regular results. here, we report a probable occurrence of an association between nasal polypectomy and css on the basis of our findings. further, extended researches are required to establish this correlation.
منابع مشابه
Churg-strauss syndrome.
First described in 1951 as an allergic and granulomatous angiitis, Churg-Strauss syndrome (CSS) is a small-vessel vasculitis. Mean age at the time of diagnosis is approximately 50 years, with a sex ratio around 1. Asthma is the central feature of CSS and precedes the systemic manifestations in almost all cases, whereas 70% of the patients have maxillary sinusitis, allergic rhinitis, and/or sinu...
متن کاملChurg-Strauss Syndrome
Pulmonary: asthma, pneumonitis and haemoptysis. Upper respiratory tract: allergic rhinitis, paranasal sinusitis, nasal polyposis. Cardiac involvement is common. [6]This includes heart failure, myocarditis and myocardial infarction. [7] Skin: purpura, skin nodules, leukocytoclastic angiitis with palpable purpura, livedo reticularis, urticaria, necrotic bullae and digital ischaemia. Renal: glomer...
متن کاملChurg-Strauss Syndrome
A 44 year old female nurse with a 20-year history of severe, steroid-dependent asthma, hypertension, hematuria, pleuritis, and sinusitis was referred from her ophthalmologist in January 2000, with the question of possible bilateral scleritis. The patient was treated with topical steroid (prednisolone acetate 6 times daily) for anterior uveitis, systemic prednisone (50mg per os) and steroid inha...
متن کاملThe Churg Strauss Syndrome
During the first half of this century, several authors reported a variant of a small vessel vasculitis that appeared similar to the then recognized polyarteritis nodosa. The condition was distinguished by a significant atopic component, in the form of allergic rhinitis, bronchial asthma, and hypereosinophilia (1). Such patients frequently had a poor prognosis, with many patients dying as a resu...
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عنوان ژورنال:
iranian journal of allergy, asthma and immunologyجلد ۸، شماره ۲، صفحات ۱۱۱-۱۱۵
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